Ancient drug curcumin impedes 26S proteasome activity by direct inhibition of dual-specificity tyrosine-regulated kinase 2

Research in mice suggests that curcumin treatment significantly reduces tumor burden in immunocompromised mice and synergizes with the therapeutic proteasome inhibitor carfilzomib to induce apoptosis in a variety of proteasome-addicted cancer cells.

2018-07-25T13:40:29+00:00